12th Bay Area Aging Meeting

Thursday, May 26, 2016
245 Li Ka Shing Center
University of California, Berkeley

9:00-9:20 Breakfast and registration
9:20-9:30 Welcome remarks

Session 1: Neurodegenerative Diseases and Parabiosis

Moderator: Danica Chen

9:30-9:45 Elena Minones-Moyano — Dubal lab (UCSF)
The X Chromosome, Aging, and Alzheimer’s Disease
9:45-10:00 Ed Liao — Haghighi Lab (Buck)
Regulation of endosomal dynamics: from synaptic homeostasis to age-dependent neurodegeneration
10:00-10:15 Lindsay Becker — Gitler lab (Stanford)
Manipulating RNA-binding protein interactions as a therapy for two related age-dependent neurodegenerative diseases: FTD and ALS
10:15-10:30 Julia Marschallinger — Wyss-Coray Lab (Stanford)
Age-related accumulation of cellular vesicles in microglia and reversal through heterochronic parabiosis
10:30-10:45 Sietske Bakker — Passegue Lab (UCSF)
No evidence for rejuvenation of old HSCs upon exposure to a young systemic environment
10:45-11:15 Coffee break

Session 2: Keynote Addresses

Moderator:Eric Verdin

11:15-11:45 Felipe Sierra (Director, Division of Aging Biology, NIA)
Recent advances in geroscience
11:45-12:15 Hening Lin (Professor, Cornell/Investigator, HHMI)
Sirtuin and novel PTMs: Possible new aging mechanisms?
12:15-12:30 Mark Collins (President, Glenn Foundation)
12:30-1:30 Lunch

Session 3: Aging-associated Deterioration and Reversal

Moderator: Pankaj Kapahi

1:30-1:45 Mike Harris — Ingolia lab (Berkeley)
Integrated Transcriptome and Proteome Analyses Reveal Organ-Specific Proteome Deterioration in Old Rats
1:45-2:00 Chen-Yu Liao – Kennedy lab (Buck)
Rapamycin reverses metabolic deficits in Lamin A/C-deficient mice
2:00-2:15 Joana Neves — Lamba & Jasper Labs (Buck)
Immune modulation by MANF promotes tissue repair and regenerative success in the retina
2:15-2:30 Kunwoo Lee – Conboy lab (Berkeley)
Genome editing in vivo with the delivery of Cas9 ribonucleoprotein and donor DNA complexed to gold nanoparticles
2:30-2:45 Sara Hagg – Hagg lab (Karolinska Institute/Stanford)
Molecular epidemiological studies of aging in a longitudinal Swedish twin cohort
2:45-3:00 Nora Yucel – Blau lab (Stanford)
Metabolic Regulation of Muscle Stem Cell Acetylation Landscape during Regeneration
3:00- 3:45 Poster Session

Session 4: Novel Aging Pathways

Moderator: Anne Brunet

3:45-4:00 Eric Sawyer — Unal (Berkeley)
Mitochondrial Network Remodeling Facilitates Organelle Inheritance in Yeast Gametogenesis
4:00-4:15 Su Liu — Kapahi lab (Buck)
SILAC analysis reveals a role of senescence associated secretory phenotype (SASP) in hemostasis
4:15-4:30 Claude Le Saux — Campisi lab (Buck)
Are senescent cells a link between aging and fibrosis in the lungs?
4:30-4:45 Chi-Kuo Hu — Brunet Lab (Stanford)
Diapause in vertebrate: a natural form of suspended animation that protects organisms from stress and aging
4:45-5:00 Yuehua Wei — Kenyon/Li labs (UCSF)
A germ cell-regulated redox signaling for somatic longevity
5:00-5:05 Closing remarks