13th Bay Area Aging Meeting

Monday, November 7th, 2016
Gladstone Institutes, 1650 Owens Street, San Francisco

8:30-9:00 Arrival/Breakfast
9:00-9:10 Welcome, Eric Verdin

Session 1

Moderator: Anne Brunet


VCP-Dependent Muscle Degeneration is Linked to Defects in a Dynamic Tubular Lysosomal Network in vivo

9:25-9:40 Geraldine Gontier- (Villeda Lab, UCSF)
9:40-9:55 Kelly Rainbolt (Frydman lab, Stanford)
Neural Stem Cell Proteostasis is Rewired Upon Differentiation and Aging
9:55-10:10 Brunilda Balliu (Montgomery Lab, Stanford)
Longitudinal study of gene expression and regulation in a Swedish population sample
10:10-10:25 Itamar Harel (Brunet Lab, Stanford)
Age-related loss of proteostasis as a driver of aging and disease in a new vertebrate model: the African turquoise killifish
10:25-10:55 Coffee Break + Poster setup

Session 2

Moderator:Tom Rando

11:00-12:50 Keynote Speaker – Peter Adams, PhD University of Glasgow, CRUK Beatson Institute
The dynamic epigenome – challenges and opportunities for healthy aging
12:00-12:15 Mark Collins (President, Glenn Foundation)
12:15-1:15 Lunch / Poster Session

Session 3

Moderator: Pankaj Kapahi

1:30-1:45 Kenneth Wilson (Kapahi & Brem Labs, Buck)
Genome-wide analysis reveals novel genetic regulators of diet-related changes in longevity and healthspan in Drosophila melanogaster
1:45-2:00 Oliver Davis (Roberto Zoncu lab, Berkeley)
Investigating novel mechanisms of mTORC1 regulation by nutrient inputs
2:00-2:15 John Newman- (Verdin Lab, Gladstone Institute )
Enhanced lifespan and cognition with ketogenic diet in aging mice
2:15-2:30 Jose Alberto, (Jon Ramsey’s lab ,UC Davis)
Effect of a very low- carbohydrate, ketogenic diet on longevity and healthspan of adult mice.
2:30-2:45 Jiashun Zheng ( Hao Lab, Stanford)
Methionine abrogates the lifespan extension and partially reverses the translational program induced by caloric restriction: identification of proteasome as a key downstream effector
2:45-3:15 Coffee Break

Session 4

Moderator: Danica Chen

3:15-3:30 Sonnet Davis (Ramanathan Lab, Buck)
Metformin inhibits Branched Chain Amino Acid (BCAA) derived ketoacidosis and promotes metabolic homeostasis in Maple syrup Urine disease
3:30-3:45 Mike Wosczyna (Rando Lab, Stanford)
Mesenchymal Stem Cells as Determinants of Tissue Aging
3:45-4:00 Hanzhi Luo (Danica Chen lab, Berkeley)
Stem Cell Aging
4:00-4:15 Jie Zhu (Lamba Lab, Buck)
Immunosuppressed retinal environment created by IL2rg knockdown promotes enhanced long-term functional integration of hESC- derived photoreceptors
4:15-4:30 Evgenia Verovskaya (Passegué Lab, UCSF)
Remodelling of multipotent progenitor pool directly contributes to hematopoietic aging.
4:30-4:45 Samantha Haller (Jasper Lab, Buck)
Tor signaling in stem cell activation and age-related stem cell loss
4:45-5:00 Poster Prizes- Joe Betts Lacroix
5:00-5:05 BAAM Organizers: Closing remarks
4:30-6:00 Receptions/ Posters