7th Bay Area Aging Meeting

November 25, 2013
Huang Engineering Center, Stanford University

8:30-9:15 Breakfast
9:15-9:30 Welcome – Stuart Kim

Session 1: Aging and Stem Cells

Moderator: Stuart Kim

9:30-9:45 Joseph Rodgers – Tom Rando Lab (Stanford)
“Where did the early birds go? Selective forces on stem cell aging”
9:45-10:00 Tandis Vazin – David Schaffer Lab (Berkeley)
“Stem cells for modeling and repair of neurodegenerative diseases”
10:00-10:15 Johanna Flach – Emmanuelle Passegué Lab (UCSF)

“Replication stress is a potent driver of functional decline in aging hematopoietic stem cells”
10:15-10:30 Deepak Lamba – Deepak Lamba Lab (Buck Institute)
“Modeling age-related Macular Degeneration using stem cells”
10:30-11:00 Coffee break
12:10pm–1:40pm Lunch/Poster Session

Session 2: Hormones and Pheromones in Aging

Moderator: Pankaj Kapahi

11:00-11:15 Lauren Broestl – Dena Dubal Lab (UCSF) “Young ovaries: a window into the aging brain”
11:15-11:30 Travis Maures – Anne Brunet Lab (Stanford)
“Males induce the untimely demise of the opposite sex in C. elegans
11:30-11:45 Christian Elabd – Irina Conboy Lab (Berkeley)
“A new age-specific circulating hormone necessary for muscle maintenance and regeneration”
11:45-12:00 Announcement from Mark Collins (Glenn Foundation for Medical Research)
12:00-1:15 Lunch

Session 3: The Influence of Stress and the Environment on Aging

Moderator: Eric Verdin

1:15-1:30 Mark Lucanic – Gordon Lithgow Lab (Buck Institute)
“A high throughput chemical screen identifies a novel activator of dietary restriction in C. elegans
1:30-1:45 Jenny Shin – Danica Chen Lab (Berkeley)
“Epigenetic blockage of ER stress prevents fatty acid liver disease”
1:45-2:00 Chong He – Brian Kennedy Lab (Buck Institute)
“Ibuprofen and its role in tryptophan metabolism and replicative lifespan in S. cerevisae
2:00-2:15 Nate Baird – Andy Dillin Lab (Berkeley)
“PAT-10 confers thermal stress resistance and longevity via cytoskeletal integrity”
2:15-2:30 Shankar Chinta – Julie Andersen Lab (Buck Institute)
“Environmental stress, astrocyte senescence, and neural stem cell dysfunction: a novel link in Parkinson’s disease?”
2:30-3:45 Coffee and Poster Session

Session 4-5: Genomic stability – Brain integrity

Moderator: Danica Chen

3:45-4:00 Luisa Tasselli – Katrin Chua Lab (Stanford)
“SIRT6 deacetylase: chromatin silencing of centromeric repeat transcripts is essential for mitotic fidelity”
4:00-4:15 Keiko Muraki – John Murnane Lab (UCSF)
“The mechanism of inhibition of double-strand break repair near telomeres in mammalian cells”
4:15-4:30 Lucas Smith – Saul Villeda Lab (UCSF)
“Beta2-Microglobulin regulates the decline in neurogenesis and cognitive function during aging”
4:30-4:45 Taeho Kim – Carla Shatz Lab (Stanford)
“A new high affinity receptor for beta amyloid”
4:45-5:00 Concluding comments and Awards
5pm Happy Hour!!