13th Bay Area Aging Meeting
Monday, November 7th, 2016
Gladstone Institutes, 1650 Owens Street, San Francisco
| 8:30-9:00 | Arrival/Breakfast |
| 9:00-9:10 | Welcome, Eric Verdin |
Session 1
Moderator: Anne Brunet
| 9:10-9:25 |
VCP-Dependent Muscle Degeneration is Linked to Defects in a Dynamic Tubular Lysosomal Network in vivo |
| 9:25-9:40 | Geraldine Gontier- (Villeda Lab, UCSF) |
| 9:40-9:55 | Kelly Rainbolt (Frydman lab, Stanford) Neural Stem Cell Proteostasis is Rewired Upon Differentiation and Aging |
| 9:55-10:10 | Brunilda Balliu (Montgomery Lab, Stanford) Longitudinal study of gene expression and regulation in a Swedish population sample |
| 10:10-10:25 | Itamar Harel (Brunet Lab, Stanford) Age-related loss of proteostasis as a driver of aging and disease in a new vertebrate model: the African turquoise killifish |
| 10:25-10:55 | Coffee Break + Poster setup |
Session 2
Moderator:Tom Rando
| 11:00-12:50 | Keynote Speaker – Peter Adams, PhD University of Glasgow, CRUK Beatson Institute The dynamic epigenome – challenges and opportunities for healthy aging |
| 12:00-12:15 | Mark Collins (President, Glenn Foundation) |
| 12:15-1:15 | Lunch / Poster Session |
Session 3
Moderator: Pankaj Kapahi
| 1:30-1:45 | Kenneth Wilson (Kapahi & Brem Labs, Buck) Genome-wide analysis reveals novel genetic regulators of diet-related changes in longevity and healthspan in Drosophila melanogaster |
| 1:45-2:00 | Oliver Davis (Roberto Zoncu lab, Berkeley) Investigating novel mechanisms of mTORC1 regulation by nutrient inputs |
| 2:00-2:15 | John Newman- (Verdin Lab, Gladstone Institute ) Enhanced lifespan and cognition with ketogenic diet in aging mice |
| 2:15-2:30 | Jose Alberto, (Jon Ramsey’s lab ,UC Davis) Effect of a very low- carbohydrate, ketogenic diet on longevity and healthspan of adult mice. |
| 2:30-2:45 | Jiashun Zheng ( Hao Lab, Stanford) Methionine abrogates the lifespan extension and partially reverses the translational program induced by caloric restriction: identification of proteasome as a key downstream effector |
| 2:45-3:15 | Coffee Break |
Session 4
Moderator: Danica Chen
| 3:15-3:30 | Sonnet Davis (Ramanathan Lab, Buck) Metformin inhibits Branched Chain Amino Acid (BCAA) derived ketoacidosis and promotes metabolic homeostasis in Maple syrup Urine disease |
| 3:30-3:45 | Mike Wosczyna (Rando Lab, Stanford) Mesenchymal Stem Cells as Determinants of Tissue Aging |
| 3:45-4:00 | Hanzhi Luo (Danica Chen lab, Berkeley) Stem Cell Aging |
| 4:00-4:15 | Jie Zhu (Lamba Lab, Buck) Immunosuppressed retinal environment created by IL2rg knockdown promotes enhanced long-term functional integration of hESC- derived photoreceptors |
| 4:15-4:30 | Evgenia Verovskaya (Passegué Lab, UCSF) Remodelling of multipotent progenitor pool directly contributes to hematopoietic aging. |
| 4:30-4:45 | Samantha Haller (Jasper Lab, Buck) Tor signaling in stem cell activation and age-related stem cell loss |
| 4:45-5:00 | Poster Prizes- Joe Betts Lacroix |
| 5:00-5:05 | BAAM Organizers: Closing remarks |
| 4:30-6:00 | Receptions/ Posters |